Updated on May 23, 2024 | Featured, Psychiatry
For a patient and their loves ones, preparing for an organ transplant is never easy, and the same holds true for someone considering donating an organ. Mount Sinai’s transplant psychiatry program is one of many resources there to help with the process and, in the end, help save lives.
Mount Sinai Transplant is a premier program for organ transplantation, offering comprehensive treatment for patients who desperately need organs such as hearts, lungs, kidneys, and livers. Among the program’s renowned specialists are transplant psychiatrists who are specially trained to help both organ recipients and living donors.

Ambika Yadav, MBBS
“Across the United States, about 100,000 people require an organ transplant. There’s a huge need,” says Ambika Yadav, MBBS, Assistant Professor, Psychiatry, at the Icahn School of Medicine at Mount Sinai, who specializes in transplant psychiatry, focusing on liver and kidney donors and recipients.
“The goal of transplant psychiatry is to mitigate whatever psychosocial risks exist so we can help as many people as possible get the organs that will save their lives,” she says.
Transplant Psychiatry at Mount Sinai
Mount Sinai’s transplant psychiatrists are based at the Recanati/Miller Transplantation Institute, where they work closely with other members of the transplant team. They provide a range of services for organ recipients and for living donors who choose to donate a kidney or portion of a liver. Those services include:
- Evaluating a patient’s suitability as a transplant donor or recipient
- Establishing treatment plans for patients with preexisting psychiatric conditions
- Helping patients develop coping skills and manage expectations around organ transplantation
- Managing psychiatric symptoms that can arise as a result of surgery or medication side effects
- Dealing with complicated emotions after transplant
Helping Organ Recipients Prepare for Transplant
All transplant recipients receive an extensive medical and psychosocial evaluation to determine their suitability for transplantation. Typically, a transplant social worker provides the initial psychosocial evaluation. But transplant psychiatrists often get involved to further assess patients and mitigate any risks.
The goal of that assessment isn’t to rule out whether a person is a suitable candidate for a new organ. Rather, the transplant psychiatrists focus on identifying factors that might cause setbacks and find ways to manage those factors.
“Our goal is always to optimize patients for organ transplant. By identifying risks, we can come up with a plan ahead of time so they can get the organ they need and continue to have a life,” Dr. Yadav says.
For example, when patients have diagnoses such as anxiety or depression, psychiatrists can work with them to develop a treatment plan to reduce the risk that symptoms will get in the way of their transplant recovery. Psychiatrists can also come up with plans to support patients with alcohol use disorder or other substance use disorders, a common history among patients with liver failure.
“In those cases, we’ll do a risk assessment of the severity of their substance use disorder and determine how we can best help prevent them from relapsing so they can be good stewards of their new organ,” Dr. Yadav says.
When possible, these meetings happen in an outpatient setting. But in many cases, patients are evaluated for transplant after they become critically ill and so are already in the hospital. “Because Mount Sinai is a major transplant center, many patients are transferred here because they are surgically complicated or otherwise high-risk,” Dr. Yadav says. She and her colleagues meet regularly with hospitalized patients to assess their needs and help them prepare for transplant.
Managing Life After Organ Transplant
Psychiatrists also help people manage issues that arise after an organ transplant. Agitation and delirium can be side effects of surgery, and immunosuppressant medications that prevent organ rejection can cause psychiatric side effects and may also interact with other psychiatric drugs in complicated ways, according to Dr. Yadav.
“Community psychiatrists may not have much experience managing those psychiatric side effects and interactions,” she says. “Once a patient is stabilized after transplant, we can refer them to a community psychiatrist and provide our recommendations for managing their treatment.”
Psychiatrists also help patients deal with complicated emotions following a transplant. Patients might feel guilty or unworthy after receiving an organ from a deceased donor. They may expect life to be completely different after a transplant and feel let down by ongoing medical challenges and other life stressors. “We can help people manage their expectations and find ways to cope,” Dr. Yadav says.
Supporting Living Organ Donors
On the other end, transplant psychiatrists play a key role in assessing living donors and helping them prepare for the procedure. Living organ donors can donate a kidney or a portion of their liver to recipients—including friends and family members, and in some cases, anonymous recipients. Psychiatrists screen patients for preexisting psychological conditions that could affect their decision and well-being, and ensure they understand the risks they’re taking.
Increasingly, living donors contribute kidneys in “paired exchanges”—for example, a donor who is not a match for his wife may donate to a stranger on the waiting list, while someone related to that stranger donates to the first man’s wife. Such paired exchanges can involve multiple steps of exchanges. “Given the intricacies and the many points at which things might not go as planned, we hold these patients to a higher standard and make sure they know what to expect,” Dr. Yadav says.
Donating an organ is a big decision. “These are people who are completely healthy, undertaking a surgical procedure with zero benefit to themselves,” Dr. Yadav says. Mount Sinai’s transplant programs go above and beyond to keep living donors’ well-being at the forefront. “Our living donor team is really special. They put the donor first, and always prioritize their needs separate from the needs of the organ recipient,” she adds.
Moving Transplant Psychiatry Forward
Dr. Yadav and her colleagues are also engaged in research to improve their approach to assessing patients and mitigating psychosocial risks.
“As a major transplant center, Mount Sinai has many complicated cases and we have a lot of data regarding our risk assessments and patients’ psychosocial outcomes,” she says. “We’re always trying to use data to come up with better assessment tools and ultimately improve outcomes for patients.”
Transplant psychiatry is a subspecialty of the Consultation Liaison Psychiatry services at the Icahn School of Medicine at Mount Sinai. Learn more about Mount Sinai Transplant and Living Donor Transplantation.
May 2, 2024 | Featured, Your Health

Hepatitis is inflammation of the liver—an organ we depend on to digest nutrients, filter blood, and overcome infection. There are many different types of hepatitis, including hepatitis A, B, C, D, and E, with symptoms that include fever, abdominal pain, nausea, jaundice (yellowing of the skin and eyes), and fatigue.
However, most people with chronic viral hepatitis do not experience any symptoms and often do not know they have the infection even while it silently damages their liver. Hepatitis B and C are among the most common types of hepatitis. While they both affect the liver, they are very different.

Douglas Dieterich, MD
In this Q&A, Douglas Dieterich, MD, Professor of Medicine (Liver Diseases) and Director of the Institute for Liver Medicine at the Icahn School of Medicine at Mount Sinai, explains the differences between hepatitis C and B, how they are transmitted and treated, who is at risk, and more.
What is the difference between hepatitis C and B?
Hepatitis C virus (HCV) and hepatitis B virus (HBV) are vastly different viruses. Hepatitis B is highly contagious through sex, using drugs with shared straws and needles, blood transfusions, and even saliva, which can put people living in the same household at risk. The good news is hepatitis B is entirely preventable with a vaccine, which has been around since 1991. The Centers for Disease Control and Prevention now recommends universal vaccination for hepatitis B for all adults under 60 who did not get vaccinated by their pediatrician starting in 1991. People over 60 can also request the vaccine and should, especially if they have ongoing risk factors. If people do get hepatitis B, there are very good drugs to control it and to suppress the virus down to zero so it doesn’t do any damage or infect others. We also have exciting clinical trials happening to study medications that can cure Hepatitis B.
Currently, there is no vaccine for hepatitis C, which is a different class of virus. It actually belongs to a class that you may have heard of—West Nile virus, dengue fever, yellow fever, and Zika, which has been in the news the last few years. None of those become chronic, however, while hepatitis C does. Over time, it can cause the same liver damage that hepatitis B can, including liver cancer, which can lead to death. The good news is, it’s now easily curable. We have fantastic new drugs for hepatitis C—most patients need to take only 8 to 12 weeks of easy-to-take pills with virtually no side effects and a 99 percent cure rate. It’s absolutely important to find out if you have hepatitis C or B because we can cure hepatitis C and control hepatitis B.
What do I need to know about hepatitis D?
Hepatitis D, also known as hepatitis Delta virus (HDV), is the most severe form of viral hepatitis. This is a type of hepatitis that can only infect people who have hepatitis B. Approximately 70 percent of people who have hepatitis Delta will develop cirrhosis (liver scarring) within 5 to 10 years of infection. This is a much higher and faster progression than for most people with hepatitis C and hepatitis B.
Hepatitis Delta can only function in a body that is also infected with hepatitis B. Not everyone with hepatitis B has hepatitis Delta, but everyone with hepatitis Delta also has hepatitis B. That’s why we recommend everyone with hepatitis B get screened for hepatitis Delta too.
New effective treatments for hepatitis Delta are coming soon and are already available to some patients, depending on their specific health situation. Our providers can screen you for hepatitis Delta and help get you onto treatment if needed.
Who is at risk for contracting hepatitis B and C, and who should get screened?
The CDC recommends all adults be screened for hepatitis B and C at least once in their life, even if they don’t think they have any risk factors. Many people have been exposed but don’t know it. The major method of transmission for hepatitis B, globally, is from mother to infant at birth. Other people who are at risk are those who have never been vaccinated—primarily people born before 1991—and we see that happening now. When people born before 1991 come in contact with people who have hepatitis B, they can catch it quite easily. Hepatitis C is more difficult to catch. The major risks for hepatitis C are having had a transfusion of blood or blood products, such as gamma globulin, before 1992, or using IV drugs or intranasal drugs. Just snorting drugs with a straw is enough to spread Hepatitis C. People who have unprotected sex—especially men who have sex with men—are also at risk for hepatitis C. It’s very important to get diagnosed early so you can get treated and cured. If you know you have ongoing risk factors, you should be screened at least once a year.
Why is hepatitis more common in New York City?
About 48 percent of the people who live in New York City were born outside of the United States. Many of those people come from countries where hepatitis B or C is endemic, and that’s the major risk factor for hepatitis B. Endemic means that a high percentage of people in an area have the disease and therefore the risk of getting the disease is high. The New York City Department of Health and Mental Hygiene estimates that 243,000 New Yorkers, or 2.9 percent of the population, have chronic hepatitis B. The Department also estimates that approximately 86,000 New Yorkers, or 1 percent of the population, have chronic hepatitis C. If we catch viral hepatitis early, we can help you prevent liver scarring and liver cancer.
What is the best way to prevent hepatitis B and C?
The best way to prevent hepatitis B is to get vaccinated for hepatitis B. The CDC now recommends everyone aged 18 to 59 be vaccinated for hepatitis B. If you weren’t vaccinated as a kid, it’s easy to check if you have antibodies to hepatitis B, or if you have hepatitis B, we can treat that. Ask your doctor about testing and vaccination.
Hepatitis C is mostly spread blood to blood. Shared needles—if you’re using IV drugs, and shared straws if you’re using intranasal drugs—things like that—are really high risk for spreading hepatitis C. Getting a tattoo or piercing from an unlicensed technician may also put you at risk if they are not properly cleaning their needles. If you are using drugs, don’t share needles, don’t share straws. And get tested for hepatitis C, because if you have it, we can cure it. Once cured, you can become reinfected with hepatitis C, so it’s very important to continue avoiding infection after getting cured, which means not sharing needles or straws and practicing safe sex, and only getting tattoos and piercings from licensed technicians.
What resources are available at Mount Sinai for screening and treatment of hepatitis?
We have numerous resources dedicated to screening and treatment of hepatitis B and hepatitis C at Mount Sinai. We’re the largest independent liver program in the country. We have liver clinics all over Manhattan and the metropolitan area—from Long Island to Westchester. Our care coordinators will support you from screening through treatment and cure, working closely with your provider to ensure you get the best care.