Grateful Patient Acknowledges Neurosurgical Team

The team involved in the treatment and care of patient Jeannie Gaffigan included, from left: Colleen Geary, OTR/L, Rehabilitation Specialist in Occupational Therapy, Department of Rehabilitation and Human Performance; Jeffrey T. Gilligan, MD, Neurosurgery Resident (PGY-5); Neha S. Dangayach, MD, MSCR; Robert J. Rothrock, MD, Chief Neurosurgery Resident (PGY-6); Leslie C. Schlachter, PA-C; Joshua B. Bederson, MD; Kurt A. Yaeger, MD, Neurosurgery Resident (PGY-5); Johanna T. Fifi, MD, Associate Professor of Neurosurgery, Neurology, and Radiology, and Associate Director, Cerebrovascular Center; Joseph Waugh, NP, Neurosurgery Intensive Care Unit; and Holly E. Oemke, Program Manager, Neurosurgery Simulation Core.

In 2017, Jeannie Gaffigan, a popular director, producer, and comedy writer, urgently needed to consult with a neurosurgeon. An MRI had revealed that the seemingly harmless symptoms that she had been experiencing, and ignoring for at least a year—including headaches, dizzy spells, and loss of hearing in one ear—were the result of a massive, life-threatening brain tumor, pushing against her brainstem. Ms. Gaffigan, the mother of five children with her husband, comedian Jim Gaffigan, feared she was going to die.

Joshua B. Bederson, MD, Professor and Chair of Neurosurgery for the Mount Sinai Health System, reassured her that he could perform complex surgery and safely remove the tumor. In a 10-hour operation, Dr. Bederson and his team—relying on years of experience combined with advanced augmented reality technologies—were able to precisely see the brain’s delicate structures, allowing Dr. Bederson to systematically separate each of the nerves and myriad blood vessels from the 6-cm pear-shaped choroid plexus papilloma, a rare type of slow-growing benign tumor.

Now, in a book that was released this month, When Life Gives You Pears, Ms. Gaffigan recounts—with characteristic humor—her extraordinary medical journey at Mount Sinai, acknowledging those who provided her with expert and compassionate care.

Jeannie Gaffigan

“There are many people involved with a patient’s neurosurgical care beyond the surgeon,” says Dr. Bederson. “In Jeannie’s case, she was helped not only by me and my immediate team, but also by neuroendovascular surgeons, neurocritical care staff, pulmonologists, otolaryngologists, physiatrists, physical therapists, and others.”

Leslie C. Schlachter, PA-C, the Department of Neurosurgery’s Chief Physician Assistant and Clinical Director, played a significant role in guiding Ms. Gaffigan through the surgical process and coordinating care across specialties. “Our relationship continues to this day with intermittent text messages where I assure her that she is on the road to an excellent recovery,” says Ms. Schlachter.

After surgery, Ms. Gaffigan spent a period of time in The Mount Sinai Hospital’s Neurosurgery Intensive Care Unit (NSICU), and she later required more hospitalization and a prolonged period of rehabilitation.

Says Neha S. Dangayach, MD, MSCR, Assistant Professor of Neurosurgery, and Neurology, and Co-Director of the NSICU, “Because Jeannie’s surgery was very complex, she required extensive neurocritical care to help her embark on the perfect trajectory for a successful recovery.” Dr. Dangayach adds, “I commend Jeannie for being a great team player, for her sense of humor, and exceptional patience with us. I also commend our team of neurointensivists, fellows, physician assistants, nurse practitioners, specialty-trained nurses, and rehabilitation specialists for providing her exceptional care throughout her weeks-long stay.”

South Nassau Communities Hospital Is Renamed Mount Sinai South Nassau

Mount Sinai South Nassau in Oceanside, New York.

South Nassau Communities Hospital—a 90-year-old institution that serves 900,000 residents on the South Shore of Long Island—will now operate as Mount Sinai South Nassau to reflect its partnership with the Mount Sinai Health System.

“The new name reflects not only the hospital’s proud history and regional geography, but also its future,” says Kenneth L. Davis, MD, President and Chief Executive Officer of the Mount Sinai Health System. “South Nassau’s team of highly skilled physicians, nurses, and support staff will now have the opportunity to expand services to the community through new synergies with Mount Sinai, including access to an array of specialists and clinical trials that have, until now, only been available by traveling into the city.”

Mount Sinai and South Nassau announced their plan to establish a partnership in January 2018 and received New York State regulatory approval in December 2018. During the past two years, administrative and clinical leaders have worked to combine the Mount Sinai Health System’s academic, clinical, and research expertise with the award-winning community-based care of Mount Sinai South Nassau. “The rebranding reflects a shared vision and collective goal to provide the highest quality of care to patients on Long Island,” says Arthur A. Klein, MD, President of the Mount Sinai Health Network.

Mount Sinai South Nassau is one of the region’s largest hospitals, with 455 beds, more than 900 physicians, and 3,500 employees. It has added new services that are growing rapidly, such as maternal fetal medicine, interventional endoscopy, and pediatric cardiology, and plans to expand its cardiac surgery, cancer care, neuroscience, and colon and rectal surgery programs. Mount Sinai South Nassau is in the midst of a $400 million long-term strategic growth initiative that will transform its campuses in Oceanside and Long Beach, New York. Richard J. Murphy, President and Chief Executive Officer of Mount Sinai South Nassau, says, “While the hospital has a new name, our legacy of serving this community and providing patients with extraordinary health care will only grow stronger as a result of our partnership with Mount Sinai.”

The Mount Sinai Hospital is ranked No. 14 nationally in the 2019-2020 “Best Hospitals” issue of U.S. News & World Report and is ranked nationally in 8 adult medical specialties. South Nassau is ranked No. 20 among the 170 hospitals in the state of New York, as well as No. 20 among the 118 hospitals in the New York metropolitan area, while its Division of Urology is ranked 35th nationally. The Mount Sinai Health System includes more than 400 ambulatory practices and other community locations, and more than 7,000 primary and specialty care physicians, as well as 200 physicians and other experts at 11 multidisciplinary practices based on Long Island.

Combined with Mount Sinai South Nassau’s roster of approximately 900 physicians and 22 ambulatory practices, Long Islanders now have access to a vast continuum of community-based specialty physician practices, including cardiology, internal medicine, primary care, men’s and women’s health, physical medicine and rehabilitation, orthopedics, cancer care, and many other services.

Mount Sinai South Nassau operates the only Trauma Center on the South Shore of Nassau County, along with Long Island’s only freestanding Emergency Department in Long Beach. The hospital also is nationally recognized for its nursing care and has received honors for orthopedic treatment and women’s care from Healthgrades, a national independent rating agency.

At the announcement of the hospital’s new name, from left: Adhi Sharma, MD, Executive Vice President for Clinical and Professional Affairs, and Chief Medical Officer, Mount Sinai South Nassau; Stephen J. Silich, Vice President, Business Development, Mount Sinai Health System; Rajiv Datta, MD, Chair of the Department of Surgery, Mount Sinai South Nassau; Arthur Klein, MD, President, Mount Sinai Health Network; Richard J. Murphy; President and Chief Executive Officer, Mount Sinai South Nassau; and Aaron Glatt, MD, Chair of the Department of Medicine, Mount Sinai South Nassau.

What Does a Brain Tumor Feel Like?

After ignoring seemingly harmless symptoms for at least a year, Emmy-nominated producer Jeannie Gaffigan was diagnosed by a medical team at The Mount Sinai Hospital with a pear-shaped brain tumor. The large mass was severely compressing her brain stem, causing headaches, dizzy spells, and a loss of hearing in one ear. She had attributed the symptoms to being a busy working mom. Her doctors wondered how she was even able to walk or talk normally.

The Neurosurgery team at Mount Sinai, headed by Joshua B. Bederson, MD, Professor and Chair of Neurosurgery for the Mount Sinai Health System, quickly scheduled surgery to remove the life-threatening mass, which turned out to be benign (non-cancerous).

Read more about Jeannie Gaffigan’s story 

 

Ms. Gaffigan’s case sheds light on the importance of paying attention to persistent symptoms. But not every dizzy spell is cause for concern.

Leslie Schlachter, PA-C, Clinical Director of Neurosurgery at The Mount Sinai Hospital, works closely with Dr. Bederson and was there to greet Ms. Gaffigan and her husband, comedian Jim Gaffigan, when they arrived looking for answers. Drawing on the numerous cases she has seen over the years, she explains which symptoms you should never ignore and why you are—probably—fine.

What specific symptoms may point to a brain tumor?

The brain is complex. It controls everything we do, allowing us to see, smell, and move. Because of this, symptoms of a brain tumor depend on where the tumor is located and what section of the brain it is pressing on. Generally, changes in your sensory, motor, or visual function that linger for more than a few days need to get checked. For example, if you have played tennis every weekend for the past twenty years and one day you cannot hold your racquet; that is a problem. Or, if you suddenly cannot see well out of your right eye, that is concerning.

I experienced dizziness for a few days last month. Should I check in with my doctor?

Nausea, vomiting, or a change in balance that lingers and does not respond to medicine warrants a visit to your doctor, especially if these symptoms are limiting your ability to function. Keep in mind: if you have a neurological condition, things are not going to get better. So, if your symptoms subside after a few days, there is likely no cause for concern.

Should I go to the emergency room if I am concerned? Will I seem like a hypochondriac?

If you are concerned, make an appointment with your medical provider first, whether that be a doctor, nurse practitioner, or physician assistant. I always tell people, you are going to get a cold, the flu, and food poisoning, and you may feel terrible. That is normal. However, if you are experiencing symptoms that progressively worsen and do   not go away, call your medical provider. Not seeking medical help is the problem.

The only time you should panic is if you are having what I call “The Worst Headache of Your Life.” If your headache is so severely debilitating that all you want to do is sleep because you feel as though your head is going to explode, seek medical assistance immediately as you may have a brain bleed.

What happens if my doctor is concerned about my symptoms? Will I see a neurosurgeon right away?

No. If your medical provider is concerned about your symptoms, he or she may recommend a CT scan or, depending on your symptoms, refer you to an ear, nose, and throat specialist or neurologist. You will only see a neurosurgeon if you have been diagnosed with a neurosurgical condition that requires intervention.

What should I do if my doctor is not taking my symptoms seriously?

Unfortunately, there are times when a patient’s concerns are not heard. And sometimes, your doctor may chalk up your symptoms to stress. The most important message I can give to patients is: Advocate for yourself. You know your body. If something does not feel right, get a second opinion.

No Laughing Matter: In a New Book, Comedy Writer and Producer Jeannie Gaffigan Explains How Mount Sinai Saved Her Life

Jeannie Gaffigan with Joshua B. Bederson, MD, Professor and Chair of Neurosurgery, Mount Sinai Health System, the surgeon she credits with saving her life. Click here to watch Jeannie Gaffigan and Dr. Bederson on CBS Sunday Morning

From the moment her doctor told her a magnetic resonance imaging (MRI) scan had revealed a large mass in her brain, Jeannie Gaffigan found her life filled with fear and anxiety—until she and her husband walked into The Mount Sinai Hospital and the office of Joshua B. Bederson, MD, Professor and Chair of Neurosurgery, Mount Sinai Health System.

Dr. Bederson and his staff quickly confirmed that she had a massive, life-threatening, benign pear-shaped tumor at the base of her skull that was severely compressing her brainstem. Just as important, they offered her a plan and a team of top-notch doctors and staff to whom she would entrust her life.

“We had hit the jackpot,” she writes of the team at Mount Sinai in her new book “When Life Gives You Pears,” in which she recounts her journey from sickness to health and the role that humor, faith, and family—plus her extended medical team—played in her recovery.

Watch: Jeannie and Jim Gaffigan tell their story on CBS Sunday Morning

Days after that first visit, Dr. Bederson removed the tumor during a 10-hour operation, one in which Dr. Bederson and his team relied on years of experience, combined with innovative augmented reality technology to systematically separate each of the nerves and myriad blood vessels from the tumor. By working above and below these nerves within the tumor and along the brainstem, eventually a complete removal of the tumor was accomplished.

Now, two years later, Jeannie Gaffigan, 49, a director, producer, and comedy writer and the wife of comedian Jim Gaffigan, is back to normal and savoring the simple pleasures of her life as a mother of five young children, still very grateful for the exceptional care she received from Dr. Bederson and many others at Mount Sinai.

“Every single person who has touched my life here has been an angel, and I just am so thankful for this institution,” she said during an emotional speech last year at a Mount Sinai fund-raising event. “Every single person who I’ve been treated by has been like the best and the top of their profession. I thank you, my husband thanks you, my five children thank you.”

In fact, she begins the acknowledgements at the end of her book by thanking by name a dozen Mount Sinai doctors, specialists, and staff members who cared for her in the weeks after surgery.

 

Learn more about the podcast

 

Her story also contains an important lesson: For at least a year, she had ignored a number of seemingly harmless symptoms, including headaches, dizzy spells, and loss of hearing in one ear. Otherwise, doctors might have found the tumor at an earlier stage, before it grew to about six centimeters, which could have reduced some of the complications and side effects from the surgery.

She had dismissed her symptoms as the result of her hectic life, mixing a career in entertainment with caring for young children. “I just compartmentalized all my symptoms because I was so busy,” she said in an interview as part of Mount Sinai’s Road to Resilience podcast. “So I just made them all their own separate things. So separately they seemed like little, mild annoyances.”

She might have continued to ignore her symptoms if not for the Gaffigan family’s physician, according to the book. During a routine checkup for her kids, Jeannie Gaffigan couldn’t hear something the doctor said. The doctor asked how long she had had trouble hearing. All Jeannie Gaffigan could say was that it had been a while. The doctor urged her to go a specialist. An ear, nose, and throat (ENT) specialist confirmed she was deaf in her left ear. Not seeing anything wrong with her ear during an examination, the doctor ordered an MRI on the chance there might be some obstruction deep inside the ear. The MRI showed a large mass in her brain.

At that point, she needed to see a neurosurgeon quickly. A dear cousin urged her to go to Mount Sinai. After a call from her ENT doctor, she had an appointment with Dr. Bederson, who was able to see her immediately, joined by his senior physician assistant Leslie Schlachter, PA-C, Clinical Director of Neurosurgery at The Mount Sinai Hospital. Looking at her MRI scan, Dr. Bederson said the tumor had probably been growing for years and was pushing against her brainstem, leading to a range of symptoms she had been feeling. Immediate brain surgery was needed to remove the tumor.

“I have just one question: Am I going to die?” she asked Dr. Bederson. Dr. Bederson said no. His response “was all that I needed. I knew everything else was going to be okay,” she writes in her book. (After the surgery, Dr. Bederson would diagnose the tumor as a choroid plexus papilloma, a rare type of slow-growing, non-cancerous (benign) tumor.)

A family photo of the Gaffigans

The surgery marked the beginning of a lengthy recovery, with her husband leading her caregiver team. Immediately afterwards, she spent about two weeks in the intensive care unit at The Mount Sinai Hospital, and then several more weeks in the hospital. She could not eat or drink because the surgery had left her unable to swallow. She left the hospital with a feeding tube, which was removed months later. Thanks to speech and swallow therapy, she has regained the ability to talk and eat.

Despite her personal ordeal, Jeannie Gaffigan is expecting something good to come out of her experience.

She had not intended to write a book; it began as notes she kept for herself. She hopes it may help others. “It’s not a textbook, but it’s something I wish that I had read going into this,” she told Mount Sinai’s podcast team.

And she and her husband have launched a campaign to help Dr. Bederson and Mount Sinai’s Department of Neurosurgery purchase the latest equipment for his operating room. Their fundraising goal: $500,000.

Study Directly Ties Caloric Intake to Inflammation

Researchers at the Icahn School of Medicine at Mount Sinai, using sophisticated, single-cell technology,have isolated the molecular underpinning that explains why short-term fasting and a low-calorie diet are beneficial to people with inflammatory and autoimmune diseases, such as atherosclerosis and rheumatoid arthritis. Until now, the connection between reduced caloric intake and improved health has been a widely held but poorly understood hypothesis that has captured the public’s attention as high-profile celebrities attest to the success of frequent fasting.

In the new study, published in the August 22, 2019, issue of Cell, the researchers, led by Miriam Merad, MD, PhD, Director of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai, were able to describe how dietary intake actually controls the quality and quantity of monocytes—a particular group of white blood cells.

The scientists found a direct link between the amount of glucose and protein in the body and the number of circulating monocytes. These white blood cells, likened to military “reserve forces,” respond to inflammatory stimuli and also play a major role in metabolic equilibrium, growth, and other processes. When digestible carbohydrates, protein, and fat were removed from the diet, the investigators found the pool of circulating monocytes decreased. Importantly, the size of the monocyte pool that was circulating in the blood depended upon the amount of carbohydrates ingested.

The study profiled 12 healthy, normal-weight volunteers 3 hours after eating and 19 hours after fasting, as well as mice that had fasted for 4 hours.

“Monocytes are highly inflammatory immune cells that can cause serious tissue damage,” says Dr. Merad. “We have seen more of these monocytes in blood circulation as Western-style eating habits have been adopted by increasing numbers of people around the world. Now that we have a better understanding of what is driving this incidence, we can work to treat it more effectively.”

Stefan Jordan, PhD, the study’s first author and a postdoctoral fellow in the Department of Oncological Sciences at the Icahn School of Medicine at Mount Sinai, says, “There is enormous potential in investigating the anti-inflammatory effects of fasting, considering the broad spectrum of diseases that are caused by chronic inflammation. Our discoveries could lay the groundwork for novel treatments in the future.”

Indeed, chronic diseases such as type 2 diabetes, metabolic syndrome, and cardiovascular disease are believed to be mostly caused by chronic inflammation. According to a study by the RAND Corp., 60 percent of Americans had at least one chronic condition and 42 percent had multiple chronic conditions as of 2014, the last year for which this data was available. In 2018, the Milken Institute released a report that stated the most common chronic diseases cost the U.S. economy more than $1 trillion annually.

One of the study’s important findings was that short-term fasting did not compromise the body’s ability to protect itself from acute infections or repair tissue, whereas starvation for 48 hours prior to infection did compromise the body’s antimicrobial immunity and ability to repair tissue.

Another finding by Dr. Merad and her team was that by activating a key cellular pathway in the liver, AMPK, they were able to regulate the number of monocytes regardless of caloric intake.

“Targeting liver energy sensors could be an innovative strategy for the prevention and treatment of chronic inflammatory and autoimmune diseases,” says Dr. Merad.

A Day of Remembrance for 9/11

Michael A. Crane, MD, MPH, right, gathered with speakers, from left, the Rev. James Hayes, MA, MDiv; the Rev. Amy Strano, MDiv; and Roberto Lucchini, MD, near a plaque outside Guggenheim Pavilion in observance of the World Trade Center attacks.

The 18th anniversary of the World Trade Center attacks was solemnly observed on Wednesday, September 11, at Stern Auditorium, in an event led by Michael A. Crane, MD, MPH, Medical Director of the World Trade Center (WTC) Clinical Center of Excellence (CCE) at the Icahn School of Medicine at Mount Sinai. More than 22,000 responders are being treated at Mount Sinai’s Center, which is the largest in the World Trade Center Health Program.

At the event, about a dozen staff teams presented videos about their roles in caring for 9/11 patients, in fields such as clinical care, billing, data management, and claims certification. “I think it’s important for us—because we work with this every day—to take a moment to feel proud of the work that we do,” Dr. Crane told the attendees. “While we will always feel the sorrow, let’s not be afraid also to celebrate the excellent work that you do.”

Speakers included Manish Arora, PhD, MPH, the Edith J. Baerwald Professor of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai; Sandra M. Lowe, MD, Assistant Professor of Psychiatry, Icahn School of Medicine, and Medical Director of Mount Sinai WTC CCE Mental Health Program; and Roberto Lucchini, MD, Professor of Environmental Medicine and Public Health, Icahn School of Medicine, and Director of the WTC CCE Data Center. Another speaker was the Rev. James Hayes, MA, MDiv, a chaplain for The Mount Sinai Hospital, who was present when the World Trade Center towers fell and spent the next year ministering at the site. “You are a blessing to every first responder and every person who spent time at Ground Zero,” Father Hayes told the attendees. “You provide us with respect and hope.”   

Mickie Brown, RN, led a session on mindfulness for staff members involved in the care of 9/11 responders. The meditation, with the theme of loving kindness, began and ended with the tone of a bell.

The event was preceded by a special mindfulness session attended by about 30 staff members of Mount Sinai’s WTC CCE. “On this day—which has left a mark in the history of our world, our country, and our personal lives—we want to honor those who have suffered and those who we have lost, and also the work we have done,” said the leader of the session, Mickie Brown, RN, Clinical Manager of Education, Mindfulness and Patient Well-Being at the Selikoff Centers for Occupational Health, home of the Mount Sinai World Trade Center Clinical Center of Excellence.

The session focused on an ancient meditation called Metta, or loving kindness, which Ms. Brown said could serve as “an antidote to anger and fear.” Participants sat in a quiet conference room and were invited to contemplate the phrases “may I be well; may I be happy; may I be free from suffering.” They were asked to gradually broaden those wishes to friends and loved ones, to strangers, to those who have done harm—to lead them toward peace and change—and finally to all beings. “Mindfulness sessions like this provide staff members with a set of evidence-based tools to maintain balance,” Ms. Brown said, “and ensure our capacity to be present to continue to serve the unique patient population that we care for.”

 

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