From left: Luis M. Isola, MD, Professor of Medicine (Hematology and Medical Oncology), and Pediatrics; Ramon Parsons, MD, PhD, Director, The Tisch Cancer Institute; Norman E. Sharpless, MD, Director, National Cancer Institute; and William Oh, MD, Deputy Director, The Tisch Cancer Institute, and Associate Director of Clinical & Translational Research for the Institute.

Aging is one of the greatest risk factors for developing cancer, which is most frequently diagnosed among people aged 65-74. But there are no simple explanations for the “multifaceted” science behind this connection, according to Norman E. Sharpless, MD, Director of the National Cancer Institute (NCI).

On Thursday, September 13, Dr. Sharpless addressed the topic in a seminar titled “The Dynamic Interplay between Cancer and Aging,” which he presented before a standing-room-only crowd in Davis Auditorium on The Mount Sinai Hospital campus. Dr. Sharpless has devoted much of his career to studying the connection between cancer and aging. Developing a better understanding of this relationship is particularly important, he said, because people over the age of 65 make up the fastest growing segment of the nation’s population.

Dr. Sharpless was invited to speak about his own research by The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, where he spent the earlier part of the day meeting with leaders of the Institute and medical school. He had lunch with postdoctoral fellows and students who work in Mount Sinai’s cancer-focused laboratories, and met with faculty and staff who oversee Mount Sinai’s Cancer Center Support Grant. The grant provides Mount Sinai with its NCI designation as one of an elite group of U.S. institutions committed to the research and treatment of cancer.

During the day’s meetings, Dr. Sharpless shared his vision for NCI programs and discussed trends in funding and cancer research. The Tisch Cancer Institute received its NCI designation for the fi rst time in 2015 and is preparing to renew the competitive grant in 2019. Since his appointment to the NCI in 2017, Dr. Sharpless has spent time visiting NCI-designated cancer centers around the country. On his recent trip to New York City, he also visited the Albert Einstein Cancer Center.

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