Angie V Ramirez Jimenez

Angie V Ramirez Jimenez is a second-year student in the Master of Science in Biomedical Data Science program. In this Q&A, she discusses why she chose the Icahn School of Medicine at Mount Sinai.

Why did you decide to study at Icahn Mount Sinai?

After completing my undergraduate degree, I came to Mount Sinai to work as a research associate in the lab of Michelle E. Ehrlich, MD, and Samuel Gandy, MD, PhD, in the Neurology Department. There I had the opportunity to work on various projects that investigate the mechanisms of neurodegenerative disorders including Alzheimer’s disease, dystonia, and Huntington’s disease, and learn about all the research opportunities that were available at Mount Sinai. The chance to learn from professors at the forefront of biomedical research made it the ideal place for me to expand my knowledge and skills.

What attracted you to study Biomedical Data Science? What about it inspires you?

My journey into Biomedical Data Science stemmed from a fascination with the intersection of biology and technology. The realization of the potential of programming to revolutionize scientific research sparked my interest in this field. I was inspired by the ability of data science to unlock insights from various biological datasets, leading to a deeper understanding of complex biological systems. The prospect of using data to drive advancements in precision medicine and ultimately improve patient outcomes motivated me to pursue a career in Biomedical Data Science.

What were some of your achievements as a master’s student?

During my time as a master’s student, I trained and worked in the Bioinformatics for Next Generation Sequencing (BiNGS) core at The Tish Cancer Institute at Mount Sinai. At the core, I was able to contribute to various projects, in addition to my own capstone project, which included assessing the effectiveness of a novel keratinocyte differentiation protocol on induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs), as well as investigating the impact of different extracellular matrix (ECM) environments on cancer cell dormancy. For my capstone project, I analyzed RNA-seq, ATAC-seq, and CUT&RUN data to dissect the epigenetic and transcriptional landscapes of hepatocellular carcinoma models.

What activities outside the classroom have contributed to your success?

I believe that my involvement in research projects outside the classroom have been pivotal to my success. As an undergrad, I went on a research trip to Costa Rica to investigate the resilience of microbial communities in Costa Rica’s rainforests post-hurricane. This was the first time I was part of real-world scientific research, and thanks to that, I saw a side of research I had not seen in the classroom—large-scale data analysis and how powerful it can be in understanding complex biological interactions.

This experience helped me realize this was something I wanted to pursue and once I started working in the Ehrlich/Gandy lab I was able to pursue my interest in bioinformatics and work alongside great postdocs who mentored me on how to do various types of analysis.

I’ve also worked at Liberty Science Center in Jersey City, New Jersey, where I taught kids how to do different lab experiences. I think working with the kids really taught me how not to make assumptions about how much people may know about a topic, which really helps me when trying to teach others. I also learned that everyone has the power to make an impact on others even when we may not realize it.

I think that just being open minded and not closing yourself off to opportunities, even when they seem very daunting or even insignificant, when they come is really what helps you learn and grow. Sometimes opportunities arise from the most unexpected places, but you will never find them if you don’t put yourself out there.

What are your plans after you have completed your degree?

I plan to continue my journey in the field of Biomedical Data Science. My goal is to help make a positive impact in the biomedical field, potentially preventing others from experiencing the loss of loved ones to diseases like cancer. In the distant future, I also hope to open a bike shop that can also serve as a sort of community center where people can connect with others and learn about bikes.

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