At Mount Sinai Morningside, Access to Clinical Trials and Novel Devices Is Addressing Disparities in the Treatment of Heart Failure

Mount Sinai Morningside, under the leadership of Sean Pinney, MD, Chief of Cardiology and an expert in heart failure, is eliminating health disparities among the communities most affected by cardiovascular disease and heart failure.

One method is to give patients access to a wide range of clinical trials that employ innovative medications and devices to detect and treat congestive heart failure.

For example, patients can benefit from a groundbreaking device that uses voice recognition to identify congestion. Patients speak into a smartphone from their homes, and special software enables doctors in the hospital to analyze their speech patterns for signs of congestion. The medical team can then act on that data to prevent future heart failure hospitalization.

One area of focus is the treatment of cardiac amyloidosis, a condition in which the body overproduces a protein that causes the heart to stiffen and eventually fail. About six percent of Black people living in New York are carriers of the gene that cause amyloidosis. Sarcoidosis, which causes pulmonary disease, heart disease, and heart arrythmias, is another condition found disproportionately in the Black population. If detected, both these conditions can be treated.

The Mount Sinai Morningside team has made it a priority to identify patients with these conditions in Harlem and Morningside Heights, and all the communities the hospital serves. Clinical trials are underway to diagnose and treat patients with more effective medications.

“These clinical trials represent the next generation of treatment for heart failure and have demonstrated their effectiveness in enabling patients to live fuller and longer lives,” said Dr. Pinney. “The Mount Sinai Morningside team is working hard to build trust for these trials and to demonstrate the potential value to those who can benefit most.”

For hospitalized patients, Mount Sinai Morningside is the lead site for a trial of aquapheresis, a treatment to remove excess fluid from patients who are experiencing a condition called fluid overload because of worsening heart failure.

One example of an innovative device is the AccuCinch® by Ancora Heart, which can be placed inside the heart with a minimally invasive procedure to reduce stress on the walls of the heart, allowing it to beat more efficiently.

The cardiology team also employs a novel ablation procedure to quiet the nerves that prevent the body’s ability to store blood, thereby preventing congestion from developing inside the chest and the lungs.

Hospitalized patients also have access to emerging devices such as a micro axial flow pump that is surgically implanted in the heart, which is used to treat patients with worsening heart failure and resulting kidney failure.

Diversity Innovation Hub Holds 2023 Pitch Day Competition Recognizing Innovation and Entrepreneurship

Stories Behind the Science: A New Way Forward With Food Allergies

A clinical trial helped a young boy overcome his peanut allergy, and the research team is gearing up for next steps

‘You Represent the Very Best’

Celebrating Mount Sinai’s 2025 Graduating Master’s Students

A Final Address

At Commencement, Dennis S. Charney, MD, reflects on a career to remember

Voices From the Class of 2025

Students reflect on Commencement Day at the Icahn School of Medicine at Mount Sinai

A Homecoming for a Mount Sinai Nurse and COVID-19 Patient

A retired nurse returns to the intensive care unit where she worked for many years and later received lifesaving care

COVID-19 Five Years Later: Reflecting. Learning. Advancing.

How Mount Sinai Health System responded to the lessons learned from the pandemic

Five Years Post-Pandemic: Here’s What We’ve Learned About Long COVID

David Putrino, PhD, explains how the work of physicians and researchers at Mount Sinai is helping patients

Expanding Services for the Community

New Mount Sinai Express Care-Queens offers expert care in a specially designed facility

Stories of Excellence

Highlighting the people at Mount Sinai and their extraordinary work on behalf of our patients

How Mount Sinai Queens Saved a Colleague’s Life

How Mount Sinai Queens Saved a Colleague’s Life

It started like any other day—until it wasn’t. On the morning of Thursday, February 20,  Frank Parlatore, Jr., a member of the Environmental Services team at Mount Sinai Queens, was preparing for his shift when he collapsed in the operating room locker room. Frank had...

read more
Why Are Vaccines Important?

Why Are Vaccines Important?

Vaccines strengthen your body’s natural defenses. They are the safest and most effective way to protect yourself and your family from many preventable diseases, according to the U.S. Centers for Disease Control and Prevention (CDC). Vaccines are one of the few ways we...

read more

Recipe: Roasted Butternut Squash Soup

This hearty butternut squash soup recipe is the perfect way to warm up this fall. This plant-based soup is easy to prepare and packed with fiber, antioxidants, vitamins, and minerals—essential nutrients that boost the immune system, improve heart health, and reduce your risk for chronic disease. Enjoy!

 

Ingredients:

2 medium butternut squash
Squash seeds
6 medium carrots
1 medium onion
4 cup water, divided
1/2 teaspoon white pepper
1 teaspoon smoked or regular paprika
1 teaspoon garlic powder
1/2 teaspoon cumin

Preparation:

Preheat the oven to 425 degrees.

Cut the butternut squash in half. Scoop out the seeds, but save them. Place the squash halves face-down on a baking sheet covered in foil and oiled. Sprinkle the squash seeds on the baking sheet to roast as a garnish for the soup. Set aside.

Peel and chop the carrots into thirds. Chop the onions into a few pieces. Place the carrot and onion pieces alongside the squash on the baking sheet. Bake in oven for 30 minutes. Remove the squash seeds, carrots and onion after about 30 minutes. Set the seeds aside separately, and set aside the carrots and onions. Continue baking the squash for another 30 minutes until the squash is soft enough to scoop from the skin.

Place the squash into a bowl and mash. Discard the shell.

Add half the butternut mash and half of the carrots and onions into a blender and blend on high. Add two cups of water and the pepper, paprika, garlic powder and cumin. Blend until smooth. Pour into a soup pot. Repeat the blending process with the remaining squash, carrots, onion and 2 cups of water. Add to the soup pot, combine blended portions. Stir and heat up before serving. Top with roasted squash seeds for crunch and flavor.

Nutrition

Entire Recipe:
330 calories
Carbohydrates: 40 g
Fat: 8.6 g
Protein: 4.6 g

Butternut squash to me just screams fall, so I am always trying to find the best version of this beloved soup so I can serve it during Thanksgiving. The flavors are a real crowd pleaser, and the roasted seeds make it a party.

Wendy Leon, Mount Sinai Health System, Volunteer

Click here to find more healthy recipes in Mount Sinai’s Calm & Fit Wellness Cookbook.

These recipes from faculty, staff, and students from across the Mount Sinai Health System celebrate the value of healthy eating and how cooking offers an opportunity to create community by bringing people together.

GOALS Employee Resource Group Event Offers Support and Dialogue for Black Men’s Mental Health

Sidney Hankerson, MD, MBA, was the keynote speaker, and led the discussion.

The Growth in Operations, Administration, and Leadership Society (GOALS) Employee Resource Group (ERG) hosted its quarterly outing at Mount Sinai’s Corporate Services Center in June to recognize National Mental Health Awareness Month.

This event, coordinated by Shawn Lee, Associate Director of Operations for the Central Billing Office at the Mount Sinai Health System, brought together about 20 Black men from across the Mount Sinai community to have a candid conversation about the importance of mental health and surmounting the stigmas on mental health care.

The event’s keynote speaker was Sidney Hankerson, MD, MBA, Vice Chair of Community Engagement and Associate Professor of Psychiatry, and Population Health Science and Policy at the Icahn School of Medicine at Mount Sinai. Dr. Hankerson, who is a nationally recognized expert at engaging faith- and community-based organizations to increase access to culturally relevant mental health care, facilitated the conversation and provided information on how to manage the challenges that Black men may encounter not only in health care but in their personal lives, as well.

Men, regardless of their race or ethnicity, have lower rates of seeking mental health services compared with women, Dr. Hankerson said. But Black men also face a complex array of socio-cultural factors, including racism and discrimination, misdiagnosis and clinician bias, and the common misconception that seeking help is a sign of weakness.

Among the tools available to support Black men’s mental health include culturally competent care, connections to religious communities that support mental health, exercise and behavioral activation, and social support. “I was pleased to see so many of our Mount Sinai brothers come together to create a sense of community for Black men,” said Reginald Miller, DVM, DACLAM, Dean for Research Operations and Infrastructure and Professor of Comparative Medicine and Surgery, and Environmental Health and Public Health at Icahn Mount Sinai. “Building a supportive network of Black males has been a main focus for GOALS.”

“We wanted to create a safe space where Black men can feel heard while also being able to connect with like-minded individuals, with whom they probably would have never met without a forum like this,” said Mr. Lee. “We look forward to expanding our GOALS network, collaborating with other groups, and aligning with system initiatives to foster equitable pathways for our members.”

To learn more about the GOALS ERG, email GOALS@mssm.edu or visit the website GOALS (Growth in Operations, Administrations and Leadership Society).

New Rubidium Generator Improves Reliability and Reduces Time for Cardiac PET Testing

Mount Sinai Morningside recently installed a new rubidium generator to facilitate a reliable source of isotopes for cardiac positron emission tomography (PET) studies.

With this update, Mount Sinai will become the leading health system in New York City offering high-quality, timely, and easy access to the entire range of advanced cardiac PET imaging. Cardiac PET testing includes three common type of studies: cardiac stress imaging with PET; cardiac PET viability imaging; and cardiac PET infection and inflammation imaging.

Cardiac stress PET myocardial perfusion imaging is the most accurate non-invasive test to diagnose obstructive coronary artery disease as well as coronary microvascular dysfunction, which is a common cause of symptoms and morbidity among patients who have ischemia with non-obstructive coronary arteries (INOCA) with continued symptoms.

Other key advantages of cardiac PET include:

  • Significantly lower radiation dose to the patient—approximately 3 mSV, or millisieverts, a unit of radiation exposure, per study, equal to about the amount of radiation a person is exposed to from natural sources over the course of a year.
  • Superior imaging technology leading to excellent image quality even among patients with unfavorable bodily characteristics such as obesity or women with large breasts or breast implants.
  • Availability of coronary artery calcium score information to detect subclinical atherosclerosis.
  • Availability of absolute myocardial blood flow quantitation, which helps to accurately diagnose flow-obstructing CAD including high-risk, multi-vessel CAD, diffuse atherosclerosis, post-heart transplant vasculopathy, and microvascular dysfunction in INOCA.
  • Increased efficiency and significantly shorter study time—a rest and stress Rb-82 PET takes about 30 minutes.

Due to these advantages, recent American College of Cardiology and American Heart Association guidelines on chest pain evaluation endorse the preferred use of cardiac PET over other stress imaging modalities.

Common indications for cardiac PET stress testing are:

  • Symptomatic patients with suspected ischemia unable to exercise or complete exercise during a treadmill test.
  • Previous poor quality stress imaging: equivocal or inconclusive results, artifact on images, patients with discordant results on angiogram and stress study.
  • Body characteristics affecting image quality: large breasts, obesity, pleural effusions, chest wall deformities.
  • High-risk patients to avoid diagnostic errors: patients with history of chronic kidney disease, diabetes, suspected left main or multi-vessel disease, extensive known CAD, suspected transplant vasculopathy, known CAD prior to high-risk revascularization.
  • Young patients with established CAD requiring testing to avoid repeat radiation exposure.
  • Situations where myocardial flow quantitation is necessary for clinical decision-making, (e.g. microvascular dysfunction and/or suspected multi-vessel disease).

Cardiac PET viability testing is the gold standard for detecting hibernating myocardium among patients with suspected ischemic cardiomyopathy and heart failure with significant CAD. Cardiac PET guided management has been shown to reduce long-term adverse cardiac events among these patients.

Cardiac infection and inflammation PET imaging is critical for the diagnosis and management of patients with suspected or known cardiac sarcoidosis, suspected prosthetic valve endocarditis, left ventricular assist device (LVAD) infections, pocket, and other cardiac device infections.

To refer a patient for a cardiac PET scan, please contact the Cardiology Department at Mount Sinai Morningside 212-636-4809 or send an email to cardiacPet-scan@mountsinai.org.

Click here for more information on the PET CT program at Mount Sinai Morningside.

Celebrating Mount Sinai’s 2022 Administrative Fellowship Graduates

Stories Behind the Science: A New Way Forward With Food Allergies

A clinical trial helped a young boy overcome his peanut allergy, and the research team is gearing up for next steps

‘You Represent the Very Best’

Celebrating Mount Sinai’s 2025 Graduating Master’s Students

A Final Address

At Commencement, Dennis S. Charney, MD, reflects on a career to remember

Voices From the Class of 2025

Students reflect on Commencement Day at the Icahn School of Medicine at Mount Sinai

A Homecoming for a Mount Sinai Nurse and COVID-19 Patient

A retired nurse returns to the intensive care unit where she worked for many years and later received lifesaving care

COVID-19 Five Years Later: Reflecting. Learning. Advancing.

How Mount Sinai Health System responded to the lessons learned from the pandemic

Five Years Post-Pandemic: Here’s What We’ve Learned About Long COVID

David Putrino, PhD, explains how the work of physicians and researchers at Mount Sinai is helping patients

Expanding Services for the Community

New Mount Sinai Express Care-Queens offers expert care in a specially designed facility

Stories of Excellence

Highlighting the people at Mount Sinai and their extraordinary work on behalf of our patients

How Mount Sinai Queens Saved a Colleague’s Life

How Mount Sinai Queens Saved a Colleague’s Life

It started like any other day—until it wasn’t. On the morning of Thursday, February 20,  Frank Parlatore, Jr., a member of the Environmental Services team at Mount Sinai Queens, was preparing for his shift when he collapsed in the operating room locker room. Frank had...

read more
Why Are Vaccines Important?

Why Are Vaccines Important?

Vaccines strengthen your body’s natural defenses. They are the safest and most effective way to protect yourself and your family from many preventable diseases, according to the U.S. Centers for Disease Control and Prevention (CDC). Vaccines are one of the few ways we...

read more

Pin It on Pinterest