Updated on Jun 30, 2022 | Research, Your Health
Guest post by Ilana Kersch, MS RD CDN, Senior Dietitian at the Mount Sinai Hospital. Ilana works as part of the inpatient liver transplant team in conjunction with the Recanati Miller Transplant Institute, and provides nutrition care for patients pre- and post-hepatobiliary surgery.
In recent decades, non-alcoholic fatty liver disease (NAFLD) has become an important cause of liver disease in the US due to its association with rising prevalence of obesity and type 2 diabetes. It is estimated that approximately 30% of the US population now has some degree of non-alcoholic fatty liver, and ~2- 5% of the population have fatty liver which has progressed to non-alcoholic steatohepatitis (NASH). If untreated, NAFLD and NASH can progress to liver cirrhosis and malignancy, and is quickly becoming a major indication for listing for liver transplant. (more…)
Updated on Jun 30, 2022 | Inside, Research
Kateri Moore, DVM, left, with graduate students Andreia Gomes and Jeffrey Bernitz
For scientists who study stem cells, the ability to produce hematopoietic stem/progenitor cells (HSPCs) in the lab and then transplant them into patients with blood disorders has been a long-sought-after goal. Recently, the field took a step closer to that milestone when researchers at the Icahn School of Medicine at Mount Sinai identified cells in the embryos and placentas of mice that are actually precursors to HSPCs. Hematopoiesis is the daily process by which the human body generates all of the different types of cells found in the blood and immunological system. (more…)
Updated on Jun 30, 2022 | Cardiology, Inside, Research, Your Health
Casey Crump, MD, PhD
Physical fitness in late adolescence may reduce the risk of developing type 2 diabetes later in life, according to a new study from the Icahn School of Medicine at Mount Sinai that appeared online in the March 8, 2016, issue of the Annals of Internal Medicine.
Researchers—led by Casey Crump, MD, PhD, Vice Chair for Research in the Department of Family Medicine and Community Health at Icahn School of Medicine at Mount Sinai—evaluated data on the aerobic capacity of 1.5 million males who were military conscripts in Sweden between 1969 and 1997. The scientists then compared the men’s aerobic capacity to their medical diagnoses that were made between 1987 and 2012, when the men were a maximum age of 62. (more…)
Updated on Jun 30, 2022 | Inside, Research, School
Mount Sinai School of Medicine Student Research Day 2016.
Five Icahn School of Medicine at Mount Sinai students were chosen to give oral presentations of their basic and clinical research projects at Mount Sinai’s 21st Annual Medical Student Research Day, on Thursday, March 10, in Stern Auditorium. Mitra Heshmati, PhD, Imikomobong Ibia, Emily Leven, Paul Peng, PhD, and Elizabeth Tarras received a prize of $250 each for their work, which was carried out under the supervision of faculty mentors: Scott Russo, PhD, Associate Professor of Neuroscience; Charles Mobbs, PhD, Professor of Medicine, Geriatrics and Palliative Medicine, and Neuroscience; Eyal Shemesh, MD, Associate Professor of Pediatrics, and Psychiatry; Joshua Brody, MD, Assistant Professor of Medicine (Hematology and Medical Oncology); and Rosanne Leipzig, MD, PhD, Professor of Medicine, Geriatrics and Palliative Medicine, and Population Health Science and Policy. Christina Wyatt, MD, Associate Director, Medical Student Research Office, moderated the oral presentations. (more…)
Updated on Jun 30, 2022 | Research, Your Health
Guest post by Alysia Johansson MS RD CDN, Clinical Nutrition Coordinator at The Mount Sinai Hospital. Alysia has been at Mount Sinai since 2011 where she works as part of the interdisciplinary Cardiothoracic ICU team. Alysia also coordinates malnutrition efforts for the Clinical Nutrition Department and will be presenting at an upcoming conference on April 21 2016 at The Mount Sinai Hospital, Malnutrition: Implementing Strategies for Medical Nutrition Therapy.
Malnutrition has been recognized as a problem in hospitalized patients for over 40 years. Malnutrition is any disorder of nutrition resulting from unbalanced or insufficient diet, increased needs, or impaired absorption, utilization, or excretion of nutrients – all in the presence or absence of inflammation. Malnutrition contributes to a multitude of poor patient outcomes including decreased function and quality of life, decreased wound healing, anemia, increased risk of infection, increased risk for developing pressure ulcers, increased risk of surgical complications, increased mortality, increased frequency of hospital admissions and increased length of hospital stay. Aside from being detrimental to care, all of these outcomes lead to higher healthcare costs. For these reasons, it is imperative that clinicians be aware of the signs of malnutrition, and take proper measures to enhance the nutritional status of their patients. (more…)
Updated on Jun 30, 2022 | Inside, Research
Investigators, from left, Samir Parekh, MD; and Deepak Perumal, PhD
Research into a novel treatment that could help extend the lives of patients with multiple myeloma—a disease in which cancerous blood cells proliferate in the bone marrow—is being advanced by scientists at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, who recently identified a new drug target called ARK5.
The Mount Sinai scientists discovered that when ARK5 is targeted simultaneously with CDK4, a pathway widely known to have a role in inhibiting multiple myeloma, the results were extremely effective in causing cell death. Their findings were published in the March 15, 2016, issue of the journal Cancer Research. (more…)
