Osteoporosis: Keep Your Bones Dense!

Remember those skeletons that hung in many of our elementary school classrooms growing up? The one component of those models is bone: humans are born with up to 270 of them! It is clearly important for us to protect this crucial framework in order to preserve a high quality of life.

One concern as we get older is osteoporosis, a condition of thin and porous bones. Aging, which we cannot prevent (at least not yet!), is the greatest risk factor for osteoporosis. Bones thin over time because the hormones estrogen and testosterone—which are important to maintaining bone density—both decline with age. We all know bone fractures can be debilitating, especially for the elderly, so, as with all medical conditions, prevention is paramount. (more…)

Understanding Your Thyroid Gland, aka “the Shield”

The thyroid gland got its name from the Greek word for “shield,” due to its physical appearance in the neck. In many ways, it acts like a shield by protecting our bodies from losing functional balance. The thyroid gland produces and releases thyroid hormone, which is crucial in regulating overall metabolism (the physical and chemical processes in the body that convert or use energy). Digestion, weight, temperature regulation and reproduction all are affected by the thyroid gland.

The thyroid gland works like a thermostat via its connection with the brain. If there is not enough thyroid hormone in the blood stream, the brain will stimulate the thyroid gland to produce and release more. Blood tests are an easy way to detect both the level of thyroid hormone circulating in the blood — generally free thyroxine (T4) — and the stimulating signal from the brain (TSH, or thyroid stimulating hormone). The most common thyroid problems involve abnormal production of thyroid hormone.

Hypothyroidism

Hypothyroidism is the term used to describe an underactive thyroid.

Symptoms

Symptoms include:

• Fatigue

• Feeling colder than usual

• Changes in skin and hair

• Weight gain

Causes

A common cause of hypothyroidism is Hashimoto’s thyroiditis, an autoimmune disorder in which cells in the body prevent the thyroid from producing and releasing enough thyroid hormone. Other causes include surgical removal of the thyroid gland for thyroid cancer; treatment of hyperthyroidism (an overactive thyroid gland) with radioactive iodine; or being born with an underactive thyroid gland.

Treatment

The treatment for hypothyroidism is to replace thyroid hormone in the form of a pill taken once a day, preferably by itself and on an empty stomach so that it is fully absorbed. The dose is easily adjusted based on blood tests.

Hyperthyroidism

Hyperthyroidism describes an overactive thyroid gland.

Symptoms

Symptoms include:

• Increased sweating

• Heart palpitations

• Increased anxiety

• Diarrhea

• Weight loss

Causes

A number of conditions can cause hyperthyroidism. Opposite to hypothyroidism, cells in the blood stream called antibodies make the thyroid gland secrete an excessive amount of thyroid hormone.

Treatments

The two most common treatments for hyperthyroidism are radioactive iodine and medication. Radioactive iodine works by destroying part of the thyroid gland to restore a normal level of thyroid hormone in the body; however, it is possible that hypothyroidism may then develop. Radioactive iodine has the benefit of generally being a more permanent treatment, although medications used to treat hyperthyroidism can be very effective in certain people, too. Just as in hypothyroidism, blood tests should be done routinely to monitor treatment.

Thyroid Cancer

Thyroid cancer can develop and, in the majority of cases, is curable by surgical removal of the thyroid gland by an experienced surgeon. Radioactive iodine may be used after surgery to destroy any small remaining cancer cells. An endocrinologist should be directly involved in monitoring care.

Extremes of thyroid function can certainly have an impact on your quality of life; the beauty is that with the correct diagnosis and management, these conditions can be greatly improved!

To find an excellent doctor who is right for you, please call our Physician Referral Service at 866.804.1007.

The Body’s Quarterback: The Pituitary Gland

Guest post by H. Marie Williams

One of my favorite roles as a physician is educating patients during the process of taking care of them. When patients come to my office for an evaluation regarding a specific condition (thyroid, diabetes, pituitary, bone) I start by asking them what they know about the disorder. Often, even if the patient has had the condition for many years, I can teach them something about how their body works. In this post, I aim to teach you all something about the pituitary gland, part of the body’s endocrine system.

Function of the Pituitary Gland

The pituitary gland is a pea-sized structure located in the brain directly behind the eyes. Despite its small size, I think of the pituitary gland as the “quarterback” of the body. This quarterback relays the signals from the “head coach”—a small section of the brain called the hypothalamus—to the rest of the glands of the body. These interactions make up the so-called hypothalamic-pituitary axis. The hormones from the pituitary gland control reproduction, thyroid function, breastfeeding, growth, our stress response and much more.

The best part of this whole system is that it makes sense. The head coach (the hypothalamus) knows what plays to call based on the feedback it gets from the rest of body. For example, if the circulating level of thyroid hormone is low, then the hypothalamus will receive this message and communicate with the pituitary gland to increase the stimulatory signal to the thyroid to produce more hormone.

When the Pituitary Gland is Compromised

Many different types of conditions can compromise the function of the pituitary gland. Some of these conditions send out excess hormone and some may cause a deficiency in a specific hormone. Of course, since the pituitary gland is the quarterback, this can cause many changes in the body.

Adenomas May Produce Extra Hormone…

A pituitary tumor is an abnormal growth in the pituitary gland. These are generally non-cancerous growths called adenomas. An adenoma may be producing extra hormone, such as prolactin, which is the hormone that regulates breastfeeding. A high prolactin level may cause breast discharge and disrupt the menstrual cycle. This condition, called a prolactinoma, can generally be treated with medication.

…Or Cause a Deficiency

Other adenomas do not produce hormone, but may affect the normal hormone production by the pituitary gland. For example, testosterone deficiency in males may be caused by a large pituitary adenoma, which has decreased the stimulatory signals to the testes.

I hope this basic overview provides you with insight into how the pituitary gland helps create balance in our complex body.

To find an excellent doctor who is right for you, please call our Physician Referral Service at 866.804.1007.

The Impact of Sleep on Appetite and Metabolism

We have all heard of “beauty sleep,” but the impact of sleep quality and quantity goes way beyond our physical appearance. Research has begun to clearly delineate the importance of getting a good nights rest on health, so maybe we should start talking about “healthy sleep.”

A few facts for you from a National Sleep Foundation Poll:

* 1 in 3 American adults report having sleep problems.

* The percentage of young American adults sleeping less than 7 hours has doubled over the last 40 years.

* Cumulative sleep loss over the work week for many adults may account to one full night of sleep loss.

What do these statistics mean to me?

Research has demonstrated that sleep deprivation negatively affects several important hormones that directly regulate our appetite and metabolism. Our bodies are innately programmed to regulate our energy balance, essentially matching the energy we take in with the energy we expend.

The yin and yang of energy balance are ghrelin and leptin. Ghrelin is a protein that is produced mainly by the stomach that stimulates appetite; it is why your stomach growls when you are hungry. On the other hand, leptin is a hormone released by fat cells that signals when you are full (sometimes it’s hard to listen to this one!). Several research studies on sleep deprivation have shown that leptin levels decrease and ghrelin levels increase in response to a lack of sleep, which causes an increase in appetite (specifically for high-calorie and high-salt food) throughout the day. In a review of long-term research studies, short sleep duration is associated with a risk of being overweight or obese in the future.

Lack of sleep has also been shown to increase the release of stress hormones, specifically cortisol, which decreases the body’s sensitivity to insulin (a regulator of blood sugar). An elevation in stress hormone levels may also elevate blood pressure, a risk factor for heart attacks and strokes. Just as lack of sleep may be risk factors for these conditions, it may also make them more difficult to control so improving sleep may also be a valuable treatment.

Living in the “city that never sleeps” can make it difficult to shut it down at night. The good news is that it will still be there when you wake up! If you have trouble falling asleep or staying asleep at night, please talk to your doctor to evaluate if there is a possible medical reason.

Good night and sleep tight!

Gregory B. Dodell, MD, is an Endocrinologist ta St. Luke’s and Roosevelt Hospitals.

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