Guest post by H. Marie Williams
One of my favorite roles as a physician is educating patients during the process of taking care of them. When patients come to my office for an evaluation regarding a specific condition (thyroid, diabetes, pituitary, bone) I start by asking them what they know about the disorder. Often, even if the patient has had the condition for many years, I can teach them something about how their body works. In this post, I aim to teach you all something about the pituitary gland, part of the body’s endocrine system.
Function of the Pituitary Gland
The pituitary gland is a pea-sized structure located in the brain directly behind the eyes. Despite its small size, I think of the pituitary gland as the “quarterback” of the body. This quarterback relays the signals from the “head coach”—a small section of the brain called the hypothalamus—to the rest of the glands of the body. These interactions make up the so-called hypothalamic-pituitary axis. The hormones from the pituitary gland control reproduction, thyroid function, breastfeeding, growth, our stress response and much more.
The best part of this whole system is that it makes sense. The head coach (the hypothalamus) knows what plays to call based on the feedback it gets from the rest of body. For example, if the circulating level of thyroid hormone is low, then the hypothalamus will receive this message and communicate with the pituitary gland to increase the stimulatory signal to the thyroid to produce more hormone.
When the Pituitary Gland is Compromised
Many different types of conditions can compromise the function of the pituitary gland. Some of these conditions send out excess hormone and some may cause a deficiency in a specific hormone. Of course, since the pituitary gland is the quarterback, this can cause many changes in the body.
Adenomas May Produce Extra Hormone…
A pituitary tumor is an abnormal growth in the pituitary gland. These are generally non-cancerous growths called adenomas. An adenoma may be producing extra hormone, such as prolactin, which is the hormone that regulates breastfeeding. A high prolactin level may cause breast discharge and disrupt the menstrual cycle. This condition, called a prolactinoma, can generally be treated with medication.
…Or Cause a Deficiency
Other adenomas do not produce hormone, but may affect the normal hormone production by the pituitary gland. For example, testosterone deficiency in males may be caused by a large pituitary adenoma, which has decreased the stimulatory signals to the testes.
I hope this basic overview provides you with insight into how the pituitary gland helps create balance in our complex body.
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