Denise Iliff received her Master of Science degree in Biomedical Science with a concentration in Systems Biology at the Icahn School of Medicine at Mount Sinai’s Graduate School of Biomedical Sciences in 2023. Under the mentorship of James Iatridis, PhD, Ms. Iliff conducted award-winning research in his Spine and Bioengineering Lab on spinal injuries and chronic pain. Dr. Iatridis is the Mount Sinai Endowed Chair in Orthopedic Research, Vice Chair for Research, and Director of Spine Research in the Leni and Peter W. May Department of Orthopedics at Icahn Mount Sinai.

In the following Q&A, Ms. Iliff discusses her experience at Icahn Mount Sinai and her career aspirations.

Why this area of study?

I graduated from the University of Kansas during COVID-19. My plan was to go to medical school, but I didn’t feel I was fully prepared. I wanted to find a job, and everything was super crazy, but I found a position in a lab at the University of Missouri-Kansas City Medical Campus. I had never had a research job, so I thought I would try it out, and I fell in love with it. I realized this would be a really good and logical next step for me, so I started exploring master’s programs in biomedical sciences that involved research. I was super excited to come to Icahn Mount Sinai because I could learn more about biology in the medical sense, while also doing research.

What were some of your achievements as a master’s student?

I was fortunate to work on two very interesting projects at the Iatridis Spine Bioengineering Lab and to present our findings at conferences. My work focuses on utilizing in vivo rat models to investigate how injuries to the intervertebral disc and endplates progress to spinal cord sensitization and chronic pain. The goal is to gain greater understanding of painful degenerative disc disease. For my thesis, I was given the incredible opportunity to create a project from beginning to end, all the prep work and everything up through defending the research. It has been an amazing experience.

I also had the opportunity to attend conferences, which is a great honor but, more importantly, I learned so much about how to network with scientists from many different backgrounds and how to present and speak to doctors and PhDs about my work and answer questions. I recently presented a talk at the the annual meeting of the Orthopaedic Research Society in Dallas, where I received the Best Podium award for spine section research. At the Philadelphia Spine Research Symposium, I presented a poster and received the Best Poster Award for outstanding scientific research in the pain, pathobiology, and crosstalk category. It’s all super exciting stuff, all thanks to the opportunities I had with Dr. Iatridis.

What are the strong points of this program?

Mount Sinai is such a strong research institution, which was very important to me. The diversity of labs is really what attracted me. Also, Mount Sinai has an incredible array of faculty from virtually all areas of science that a student would want to pursue.

As I read up on the program, I realized that there was a strong sense of community. I was one of the directors of the Master of Biomedical Science mentorship program, where second-year students mentor the first-years. That was a very important program for me when I came here because I was moving from Kansas to New York just as things were starting to open up again after COVID-19. Of course, the administration looks out for us, but students can offer other students a different perspective on the ins and outs. It’s an incredible program that helps orient students from undergrad or wherever they’re at in life to grad school. This program is a really good part of Mount Sinai.

What’s next?

I’m going to continue my research in the Iatridis Spine Lab as a research assistant because I still have more questions I want to answer in my project. After that, I’ll apply to physician assistant (PA) school. I enjoy patient-facing work and I think becoming a PA in a surgical specialty would be a good fit for me.

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