Ananya Parthasarathy, MSBS
Ananya Parthasarathy, MSBS, a first-year student in the PhD in Biomedical Sciences program at the Icahn School of Medicine at Mount Sinai, recalls developing an interest in immunology while growing up in India, including becoming involved in a project to investigate bacterial contents in Indian street foods.
She completed her Master of Science in Biomedical Science at the Icahn School of Medicine in June 2025, and is now continuing to work in the Immunology Multidisciplinary Training Area in the lab of Karen Edelblum, PhD, studying intraepithelial lymphocytes. Before this, she completed her bachelor of science, with honors, in biology at Azim Premji University in Bengaluru, India, where she gained research experience working with bacterial and cnidarian model organisms.
In this Q&A, she discusses why she chose Mount Sinai, the focus of her research in the immune system, and her career aspirations.
Why did you choose to study at Mount Sinai?
I chose to study at Mount Sinai because of the strong research focus of the MSBS program, particularly the wide array of research opportunities in studying immune functioning at barrier sites. Through the MSBS program, I gained not only theoretical knowledge from immunology elective courses, but also invaluable research experience in working with mouse models and using a variety of experimental techniques to study immune functioning in the small intestine.
What were some of your accomplishments during your time in the Master of Science in Biomedical Science (MSBS) program?
During my time in the MSBS program, I had multiple opportunities to present my research to faculty and my peers to receive feedback on my project. In doing so, I received awards such as best presentation at the MSBS Research Symposium in June 2024, and best poster presentation at the Pathology Research Day in May 2025. Outside of Mount Sinai, I attended the American Physiology Society Summit in April 2025, where I was awarded a Research Recognition Award and a Distinguished Abstract Award. Towards the end of my MSBS journey and the start of my PhD, I applied for and received the Society for Mucosal Immunology Technique-Sharing Travel Grant, which will contribute to my PhD project in 2026.
How did the MSBS program prepare you to apply for a PhD program?
The research and academic experience I gained during the MSBS program prepared me for PhD applications. Being part of PhD-level courses delving into fundamental concepts of biomedical science and immunology ensured I had a strong foundation of theoretical knowledge to conduct research. The exposure to multiple research techniques and the resources available at Mount Sinai allowed me to perform independent research and write a thesis for my MSBS degree, which ultimately prepared me for research as a graduate student.
Why continue your education at Mount Sinai with a PhD in Biomedical Sciences?
I enjoyed working in the Edelblum Lab, which is the primary reason I chose to continue my education at Mount Sinai. During the MSBS program, I completed all the academic requirements for the PhD in Biomedical Sciences, which allowed me to jump straight into full time research as a first-year PhD student. Additionally, the multitude of opportunities at Mount Sinai to present one’s research, as well as the accessibility and availability of resources to answer a wide array of research questions, encouraged me to continue my education at Mount Sinai. I also appreciate the collaborative nature of the immunology and graduate student departments at Mount Sinai, and was keen to continue working in such a supportive environment.
What made you interested in the immunology training area?
I have always been interested in understanding how bacteria influence the human body, particularly the immune system. Growing up in India, I was no stranger to conversations about the hygiene hypothesis and the importance of probiotics to the gut microbiome; these conversations made me interested in understanding how microbes in the human body can influence immune functioning at steady state, as well as how this can change in the context of disease. I interned at a microbiology lab in high school to investigate bacterial contents in Indian street foods, and conducted research for my undergraduate thesis on how skincare products affect the human skin microbiome.
What is the focus of your research?
My research in the Edelblum lab explores the role of gd intraepithelial lymphocytes (IEL) in intestinal homeostasis and inflammatory bowel disease (IBD). As an MSBS student, I studied the role of CD47 in gd IEL migration, and am finishing up this project to publish soon. For my PhD, I am investigating regulators of gd IEL activation and migration at steady state, focusing on the role of CD103 in signal transduction.
What are your plans after you complete your PhD?
After my PhD, I intend to continue conducting research in immune functioning at barrier sites, whether that be in industry or academia. As a first-year student, I look forward to gaining more experience in academic research, as well as in teaching and mentoring, to better understand the trajectory of my scientific career post graduate school.