Creatine Can Help You Build Muscle—Here’s How

Creatine is a natural compound found in meat and popular supplements that can help you build muscle, improve strength, and boost workout performance. Whether you’re a fitness enthusiast or just starting strength training, creatine can support your goals—but it works best when combined with proper exercise and nutrition.
“Creatine is not a magic pill—it only works when combined with consistent strength training, adequate protein, and healthy lifestyle habits,” says Taylor Stein, Associate Researcher and Registered Dietician with the Mount Sinai Physiolab, which provides personalized health and wellness recommendations based on unique assessments that capture your personal metabolic and physiological data.

Taylor Stein, RD
In this Q&A, Ms. Stein explains the basics on using creatine supplements to help build strength—while stressing that you should check with your doctor on what is right for you.
What are the benefits of creatine?
Creatine has been studied for a range of possible effects. Research suggests it may
- Enhance exercise performance and recovery
- Support cognitive function, especially in older adults
- Show potential in healing traumatic brain injuries
- Improve blood sugar management and overall metabolic health
The extent of these benefits can vary. Speak with your doctor to see if creatine supplements are right for you.
What about risks?
If you take creatine appropriately, there are few known risks. However, you should be aware of the potential that it could result in:
- Falsely elevated creatinine levels, which may raise concerns about kidney function. (It’s important to tell your doctor if you are using creatine or any other supplement.)
- Possible gastrointestinal side effects—such as nausea, bloating, or stomach discomfort—especially when starting. This is usually temporary and can be improved by adjusting the dosage.
What are the best sources of creatine, and how much do I need?
Creatine is naturally found in protein-rich foods, primarily fish, beef, and pork. A four-ounce (113g) serving of prepared beef or fish provides roughly 0.5 grams of creatine, while chicken, turkey, and other poultry contain smaller amounts.
The recommended daily dose is about five grams. To reach that amount through food alone, you’d need around 40 ounces of cooked protein daily—an unrealistic amount for most people. That’s why supplementation often makes more sense.
If I supplement, is there an ideal way to take it?
Creatine is best absorbed as creatine monohydrate (the form with the most research support) and does not require other foods for effective absorption. It usually comes in powder form, though gummies are available. Some people find the powder gritty, so I recommend mixing it into a warm beverage to dissolve it better. It’s water-soluble and doesn’t need to be combined with other foods.
Are protein and strength training necessary when taking creatine, and why?
Yes. Creatine helps ATP (adenosine triphosphate), which provides the energy for many processes within living cells, which in turn powers your muscles for contractions, allowing for improved strength and workout performance. Taking creatine can amplify the effects of physical activity, but on its own won’t do much if you are not exerting yourself in some way. Without strength training and adequate protein, creatine supplementation won’t lead to significant results.
How much protein and strength training should I do weekly?
The general recommendation is at least two strength-training sessions per week, targeting all major muscle groups (including your quads, glutes, hamstrings, and upper back).
Most people need at least 90 grams of protein a day for muscle growth, but needs vary widely depending on your body weight, goals, and whether you follow a vegetarian or vegan diet, which can include less protein per serving compared to a diet that contains meat.
How much creatine supplements should I take per day for muscle growth?
Most creatine products—powders or gummies—come in five-gram doses, which is the typical daily recommendation. Sometimes a short-term “loading period” is suggested: 20 grams per day, divided into four doses, for about five days, to reduce potential stomach upset. After that, continue with a maintenance dose of five grams daily. The reason for the loading period is that muscles can store creatine.
Does creatine work differently for women and men?
Yes, there are some differences. Some research suggests women may have lower creatine storage capacity, so the loading phase may be especially beneficial for them. For women in menopause, declines in estrogen reduce the body’s ability to build muscle. Research shows supplementation can improve exercise performance, muscle growth, recovery, and even support bone health during menopause.
There’s also some evidence supporting benefits for bone mineral density and cognitive function in older women.

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