Uncovering a Stronger Link Between Obesity and Genes

Researchers from Icahn School of Medicine at Mount Sinai, participating in the largest genetic study yet on obesity, have helped uncover stronger links between genes and body weight and body fat distribution.

The trailblazing discoveries were published in two companion papers in the February issue of the journal Nature, and were the result of a four-year international research project conducted by the Genetic Investigation of Anthropometric Traits (GIANT) consortium. Other key participating institutions included the Broad Institute of the Massachusetts Institute of Technology and Harvard University, the University of Michigan Health System, and the University of North Carolina School of Medicine. (more…)

Restorative Surgery That Patients Can Smile About

Joshua D. Rosenberg, MD, Assistant Professor of Otolaryngology at Icahn School of Medicine at Mount Sinai, is one of only a handful of U.S. surgeons who is using an innovative new procedure to restore the ability to smile in patients with facial paralysis.

The procedure, called cranial nerve V and VII transfer, helps to ameliorate the disfiguring effects of severe Bell’s palsy and, to a lesser extent, certain head and neck cancers. It calls for the surgeon to reroute the patient’s robust masseter nerve—which activates the chewing muscles—in order to power the paralyzed facial nerves and restore facial muscle function, specifically the muscles involved in smiling. (more…)