Novel Study Links High-Sugar Diet to Heart Disease

A novel study of high-sugar consumption in Drosophila fruit flies is leading researchers at Icahn School of Medicine at Mount Sinai to a greater understanding of diabetes-related heart disease, and to therapeutic targets that could ultimately prevent arrhythmia, fibrosis, and other serious heart conditions.

The research—led by Ross L. Cagan, PhD, Professor of Developmental and Regenerative Biology, and Associate Dean of the Graduate School of Biomedical Sciences—was conducted in partnership with scientists from the Sanford-Burnham Medical Research Institute in California, and published online in the January 10 issue of PLOS Genetics.

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A New York Times Tribute to Nurse Sylvie Jacobs

Sylvie Jacobs, BSN, RN, CPAN, a post-anesthesia care unit (PACU) nurse at The Mount Sinai Hospital, recently was honored with the prestigious New York Times Tribute to Nurses Award for her leadership and commitment to excellence in clinical care.

Ms. Jacobs, who has been a Mount Sinai nurse for 34 years, and has worked in the PACU since 1987, serves as a Magnet Champion, co-chair of the Perioperative Professional Practice Committee Council, and editor of The Mount Sinai Hospital Magnet Newsletter for nurses.

Recently, Ms. Jacobs participated in a Qualitative Research Project to help PACU nurses improve their skills in conflict resolution. She also was instrumental in developing an educational tool that helps novice nurses determine if patients are ready for discharge.

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Department of Psychiatry Opens New Center

The Department of Psychiatry at Icahn School of Medicine at Mount Sinai has opened a new center to investigate and treat tics, obsessive compulsive disorder (OCD), and related disorders, which are estimated to affect more than 2 million people in the United States. The new center, at 1240 Park Avenue and 96th Street, serves patients in a clinical setting that is located down the hall from a research facility that will conduct clinical trials, genetic analysis, and functional brain imaging to learn more about the disorders.

Operated by the Division of Tic, Obsessive-Compulsive, and Related Disorders (DTOR), the center “is in the vanguard of academic psychiatry because it embraces the concept that tic disorders and OCD frequently overlap and are life-cycle disorders, not separate child and adult disorders,” says Wayne Goodman, MD, Chairman of the Department of Psychiatry at Icahn School of Medicine, and the Esther and Joseph Klingenstein Professor of Psychiatry. “We are among the first medical centers to put this important concept into practice in a way that improves patient care and research.”

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Mount Sinai Advances Research into Diabetes and Heart Disease

Valentin Fuster, MD, PhD, Director of Mount Sinai Heart, presented landmark research on diabetes and heart disease at the American Heart Association (AHA) Scientific Sessions 2012. During the conference, the AHA also honored Dr. Fuster with its 2012 Research Achievement Award for his many significant contributions to cardiovascular medicine.

“With a laser-like focus on translational research, Dr. Fuster has added greatly to our understanding of the pathogenesis of coronary artery disease and thrombosis,” says AHA President Donna Arnett, PhD, MSPH. “Among his laboratory’s provocative advancements in medical science are numerous ‘firsts,’ including the original understanding of the role of platelets in heart disease and the revelation that plaque composition plays a crucial role in propensity for a heart lesion to rupture.”

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New Device Helps Paralyzed Patients Walk Again

A wearable, battery-powered robot called the Ekso™, or exoskeleton, is helping paralyzed patients walk again at The Mount Sinai Hospital’s new Rehabilitation Bionics Program, the only program in New York State that uses this device.

The Ekso, manufactured by Ekso Bionics, based in Richmond, California, is strapped over the patients’ clothing, and enables them to stand and walk with the help of a microprocessor that controls movement and a battery that provides power.

“Patients find it extremely gratifying to stand up and ambulate,” says Kristjan T. Ragnarsson, MD. “With this device, the power comes from a rechargeable battery that is carried in a backpack, and it allows patients to walk in a more natural way.” He says patients report that it is much less strenuous to walk with the device than with traditional leg braces.

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Study Finds Food-Allergic Children Subject to Bullying

Children with food allergies are frequently bullied by classmates but experience less psychological distress when their parents are aware of it, according to researchers at The Mount Sinai Medical Center, who surveyed 251 families during their visits to Mount Sinai’s Jaffe Food Allergy Institute in 2011.

The study—published online in the December 24, 2012, issue of Pediatrics—found that as many as 45.4 percent of the children, ages 8-17, reported being bullied, and 31.5 percent reported that food allergy was the reason.

“Parents and clinicians need to ask children with food allergies if they have been bullied,” says the study’s lead author Eyal Shemesh, MD, Chief of the Division of Behavioral and Developmental Health in the Department of Pediatrics at The Mount Sinai Medical Center. “Bullying is prevalent. Kids often don’t tell their parents, and it is important to know this is an issue.”

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