Second-Hand Smoke More Pervasive Than People Think

Many people who are exposed to second-hand cigarette smoke on a day-to-day basis do not realize it, according to newly published research by physicians at the Icahn School of Medicine at Mount Sinai. Yet exposure to this carcinogen carries an increased risk for heart disease and lung cancer, and mortality by an average of three years, exceeding even that of former smokers who are not exposed.

These were among the findings reported by Raja M. Flores, MD, and Emanuela Taioli, MD, PhD, in a study that appeared in the October issue of Carcinogenesis. (more…)

Research Reveals New Insights Into the Preclinical Stages of Inflammatory Bowel Disease

Study researchers Jean-Frédéric Colombel, MD, and Joana Torres, MD, postdoctoral fellow, Department of Medicine (Gastroenterology)

Study researchers Jean-Frédéric Colombel, MD, and Joana Torres, MD, postdoctoral fellow, Department of Medicine (Gastroenterology)

Years before inflammatory bowel disease (IBD) is diagnosed and symptoms exist, biomarkers are already circulating that can help predict risk not only of disease development but also of complications, according to recent findings by Mount Sinai scientists and partner organizations. For the first time, researchers found that these markers, in the form of antimicrobial antibodies, were present in serum up to six years before diagnosis of IBD, and that the higher number of antibodies indicated a greater chance of complications at or around the time of diagnosis. (more…)

EANS 2014: Virtual Reality Simulations in Brain Surgery

Anthony Costa PhD, Dr. Errol Gordon, Dr. Joshua Bederson and Zach Lorsch

Anthony Costa PhD, Dr. Errol Gordon, Dr. Joshua Bederson and Zach Lorsch

Mount Sinai’s Neurosurgery team and other presenters pose a critical question: What if your surgeon already did your surgery before you came to the operating room?

Neurosurgeons, residents and researchers congregated in the historic city of Prague to discover the latest developments, innovative techniques, and advanced practices in neurosurgery at the European Association of Neurosurgical Societies (EANS). Kicking off the educational activities in this scientific arena was Joshua B. Bederson, MD, Chair of Neurosurgery, who moderated, presented at, and helmed the Virtual Reality Simulations and Augmented Reality Applications in Brain Surgery pre-course, alongside several of his team members and neurosurgery experts from around the globe. Together they sought to answer a question posed by Bernard R. Bendok, MD, Professor in Neurological Surgery at Northwestern University Feinberg School of Medicine, in his Overview of Simulation in Neurosurgery presentation, ‘What if your surgeon already did your surgery before you came to the operating room?’ (more…)

Advancing Treatment for Rare Endocrine Disorder

At the seminar, William B. Inabnet III, MD, Chairman, Department of Surgery, Mount Sinai Beth Israel and Mount Sinai Brooklyn, far right, gathered with, from left: Hyunsuk Suh, MD, Assistant Professor, Surgery; patient Linda Annicchiarico; and Linda Hageman, RN, Founder, American Multiple Endocrine Neoplasia Support group.

At the seminar, William B. Inabnet III, MD, Chairman, Department of Surgery, Mount Sinai Beth Israel and Mount Sinai Brooklyn, far right, gathered with, from left: Hyunsuk Suh, MD, Assistant Professor, Surgery; patient Linda Annicchiarico; and Linda Hageman, RN, Founder, American Multiple Endocrine Neoplasia Support group.

Patients and caregivers from around the globe gathered to learn about the latest surgical approaches, including minimally invasive, endoscopic, and robotic techniques, to treat multiple endocrine neoplasia—a rare inherited condition that affects the body’s network of hormone-producing glands—at a recent seminar hosted by the Mount Sinai Department of Surgery. Mount Sinai is recognized as a national leader in treating this disorder. The event was organized by the American Multiple Endocrine Neoplasia Support group. Participants were able to interact with surgeons, endocrinologists, and geneticists from the Mount Sinai Multiple Endocrine Neoplasia Integrated Team, as well as with visiting faculty from the MD Anderson Cancer Center. For additional information, visit: www.mountsinai.org/care/surgery/services/endocrine-surgery.

The Tisch Cancer Institute Receives a $10 Million Grant to Study Acute Graft-Versus-Host Disease

James Ferrara, MD, DSc

James Ferrara, MD, DSc

Physician-scientists at The Tisch Cancer Institute have been awarded $10 million from the National Cancer Institute to continue their novel research into therapies that improve the standard of care for patients who develop acute graft-versus-host disease (GVHD) following bone marrow transplantation. Bone marrow transplantation (BMT) is often successfully used to treat diseases such as leukemia and lymphoma. Acute GVHD, which affects approximately 50 percent of patients, occurs when the donor’s immune cells attack the patient’s tissues, producing potentially fatal results. (more…)

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